Fig. 1 · Structure
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TH-Z93
FPPS Inhibitor
TH-Z93 is a potent farnesyl pyrophosphate synthase (FPPS) inhibitor, demonstrating an IC50 of 90 nM. This bisphosphonate compound exhibits lipophilic properties, facilitating its efficacy in modulating mevalonate pathway activity. TH-Z93 is applicable in research exploring cholesterol biosynthesis and the effects of isoprenoid synthesis inhibition in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2260887-09-8 |
| Applications | FPPS Inhibitor |
| Formula | C12H22N2O7P2 |
| Molecular Weight | 368.26 |
| SMILES | O=P(O)(C(P(O)(O)=O)NC1=NC=CC(OCCCCCC)=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.