Thalidomide-O-PEG5-alkyne is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN) ligand and a polyethylene glycol (PEG) linker. This compound is designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs), enabling targeted degradation of specific proteins within cellular contexts. Its use is essential in research applications focusing on targeted protein degradation and the modulation of protein levels for therapeutic purposes.
Thalidomide-O-PEG5-alkyne is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN) ligand and a polyethylene glycol (PEG) linker. This compound is designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs), enabling targeted degradation of specific proteins within cellular contexts. Its use is essential in research applications focusing on targeted protein degradation and the modulation of protein levels for therapeutic purposes.
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