Fig. 1 · Structure
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THDP17
Glutaminase Inhibitor
THDP17 is an orally active inhibitor of glutaminase, a key enzyme in the glutamine metabolic pathway. By inhibiting glutaminase, THDP17 effectively reduces ammonia production, making it a valuable tool in studying conditions associated with elevated ammonia levels. This compound is particularly relevant for research in metabolic disorders and cancer metabolism, where glutamine dependence plays a critical role.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 104741-27-7 |
| Applications | Glutaminase Inhibitor |
| Formula | C12H16N2S |
| Molecular Weight | 220.33 |
| SMILES | S=C(NC/C=C(C)/C)NC1=CC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.