Thiazolobenzimidazole

Catalog No.: A51536
HIV-1 Reverse Transcriptase Inhibitor
Thiazolobenzimidazole is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase. It effectively inhibits HIV-induced cytotoxicity and viral replication in various human cell lines, making it a valuable compound for research on HIV therapy and antiviral drug development. Its mechanism of action offers insights into potential therapeutic strategies against HIV-1 infection.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThiazolobenzimidazole is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase. It effectively inhibits HIV-induced cytotoxicity and viral replication in various human cell lines, making it a valuable compound for research on HIV therapy and antiviral drug development. Its mechanism of action offers insights into potential therapeutic strategies against HIV-1 infection.
Product Information
Catalog NumA51536
FormulaC15H10F2N2S
Molecular Weight288.32
CAS Number138226-12-7
SMILESFC1=C(C2SCC3=NC4=CC=CC=C4N32)C(F)=CC=C1
SynonymsNSC-625487
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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