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Thio-acridone

Photosensitizer

Thio-acridone (SACD) is a photosensitizer that generates a long-lived triplet state upon excitation with 470 nm visible light. This process leads to the production of singlet oxygen, causing damage to the structures and functions of target cells, including cancer cells. Additionally, Thio-acridone acts as a CDK4/Cyclin D1 inhibitor, exhibiting an IC50 of 2 µM. Its dual mechanism underscores its potential utility in cancer research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	6540-78-9
Applications	Photosensitizer
Formula	C₁₃H₉NS
Molecular Weight	211.28
Synonyms	SACD
SMILES	S=C1C2=C(NC3=C1C=CC=C3)C=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.