Thiocoraline is a natural depsipeptide derived from the marine bacterium Micromonospora, exhibiting significant antitumor activity. It demonstrates potent inhibitory effects with IC50 values of 0.002 μg/mL in P388 and MEL-28 cells, as well as 0.002 μg/mL in A549 and 0.01 μg/mL in HT-29 cells. Additionally, Thiocoraline exhibits strong antimicrobial properties against Gram-positive bacteria, making it a valuable reagent for cancer and microbiology research applications.
Thiocoraline is a natural depsipeptide derived from the marine bacterium Micromonospora, exhibiting significant antitumor activity. It demonstrates potent inhibitory effects with IC50 values of 0.002 μg/mL in P388 and MEL-28 cells, as well as 0.002 μg/mL in A549 and 0.01 μg/mL in HT-29 cells. Additionally, Thiocoraline exhibits strong antimicrobial properties against Gram-positive bacteria, making it a valuable reagent for cancer and microbiology research applications.
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