Thiofluor 623 is a fluorescent probe designed for the selective sensing and bioimaging of thiols. It operates on a turn-on mechanism, becoming highly fluorescent upon reaction with thiols, which cleave the probe to release a red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm). Notably, Thiofluor 623 exhibits excellent selectivity against interference from nitrogen and oxygen nucleophiles, making it an ideal tool for biological applications that require sensitive detection of thiol compounds.
Thiofluor 623 is a fluorescent probe designed for the selective sensing and bioimaging of thiols. It operates on a turn-on mechanism, becoming highly fluorescent upon reaction with thiols, which cleave the probe to release a red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm). Notably, Thiofluor 623 exhibits excellent selectivity against interference from nitrogen and oxygen nucleophiles, making it an ideal tool for biological applications that require sensitive detection of thiol compounds.
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