Fig. 1 · Structure

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Thiol-PEG1-acid

PEG Derivative

Thiol-PEG1-acid is a PEG derivative featuring a thiol group (-SH) and a carboxylic acid (-COOH) terminal. The thiol group exhibits high reactivity, enabling the formation of stable covalent bonds with a variety of molecular targets. The carboxylic acid functionality further enhances its utility by facilitating amide bond formation with amines and ester bonds with alcohols. This compound is valuable in bioconjugation applications, such as the development of targeted therapeutics and the modification of biomolecules for improved stability and solubility.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1260092-48-5
Applications PEG Derivative
Formula C5H10O3S
Molecular Weight 150.20
Synonyms SH-PEG1-COOH
SMILES
O=C(CCOCCS)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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