Fig. 1 · Structure
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Thiol-PEG2-t-butyl ester
PROTAC Linker
Thiol-PEG2-t-butyl ester is a polyethylene glycol (PEG)-based linker specifically designed for PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound features a thiol functional group, enhancing the conjugation efficiency and stability of the PROTAC molecule. Its primary applications include the development of targeted protein degradation strategies in cellular and molecular biology research, facilitating investigations into protein function and regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1398044-50-2 |
| Applications | PROTAC Linker |
| Formula | C11H22O4S |
| Molecular Weight | 250.35 |
| SMILES | SCCOCCOCCC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.