Fig. 1 · Structure
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Thiol-PEG2-thiol
PROTAC Linker
Thiol-PEG2-thiol is a polyethylene glycol (PEG) linker designed for use in the development of PROTAC (proteolysis-targeting chimera) compounds. This bifunctional reagent facilitates the synthesis of PROTACs by enabling the conjugation of target proteins to E3 ligase, thereby promoting targeted protein degradation. Its unique structure enhances solubility and biocompatibility, making it a valuable tool in chemical biology and drug development research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14970-87-7 |
| Applications | PROTAC Linker |
| Formula | C6H14O2S2 |
| Molecular Weight | 182.30 |
| SMILES | SCCOCCOCCS |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.