Thiol-PEG2-thiol

Catalog No.: A81584
PROTAC Linker
Thiol-PEG2-thiol is a polyethylene glycol (PEG) linker designed for use in the development of PROTAC (proteolysis-targeting chimera) compounds. This bifunctional reagent facilitates the synthesis of PROTACs by enabling the conjugation of target proteins to E3 ligase, thereby promoting targeted protein degradation. Its unique structure enhances solubility and biocompatibility, making it a valuable tool in chemical biology and drug development research.
Grouped product items
Size Price Stock Qty
1mg
$20.00
In stock
25g
$25.00
In stock
50g
$30.00
In stock
100g
$40.00
In stock
500g
$70.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThiol-PEG2-thiol is a polyethylene glycol (PEG) linker designed for use in the development of PROTAC (proteolysis-targeting chimera) compounds. This bifunctional reagent facilitates the synthesis of PROTACs by enabling the conjugation of target proteins to E3 ligase, thereby promoting targeted protein degradation. Its unique structure enhances solubility and biocompatibility, making it a valuable tool in chemical biology and drug development research.
Product Information
Catalog NumA81584
FormulaC6H14O2S2
Molecular Weight182.30
CAS Number14970-87-7
SMILESSCCOCCOCCS
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2