Fig. 1 · Structure

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Thiol-PEG4-NH2 hydrochloride

PROTAC Linkers

Thiol-PEG4-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a thiol group which facilitates the conjugation to target proteins, enhancing the development of targeted degradation strategies. It serves as a crucial component in creating PROTACs for studying protein regulation and degradation pathways in cellular models.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2762393-21-3
Applications PROTAC Linkers
Formula C10H24ClNO4S
Molecular Weight 289.82
Synonyms SH-PEG4-NH2 hydrochloride
SMILES
SCCOCCOCCOCCOCCN.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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