Fig. 1 · Structure
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THP-PEG1-alcohol
PROTAC Linker
THP-PEG1-alcohol is a polyethylene glycol (PEG) based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its unique structure facilitates efficient conjugation between target proteins and E3 ligases, enhancing the targeted degradation of specific cellular proteins. This reagent is essential for researchers exploring targeted protein degradation and developing novel therapeutic strategies in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2162-31-4 |
| Applications | PROTAC Linker |
| Formula | C7H14O3 |
| Molecular Weight | 146.18 |
| SMILES | OCCOC1OCCCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.