Fig. 1 · Structure

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THP-PEG10-THP

PROTAC Linkers

THP-PEG10-THP is a PEG-based PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the solubility and stability of PROTACs, enabling the targeted degradation of specific proteins in cellular systems. THP-PEG10-THP is essential for researchers investigating protein regulation and therapeutic strategies for various diseases through targeted ubiquitination and proteasomal degradation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 42749-29-1
Applications PROTAC Linkers
Formula C30H58O13
Molecular Weight 626.77
SMILES
C1(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC2CCCCO2)CCCCO1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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