THP-PEG10-THP

Catalog No.: A83456
PROTAC Linkers
THP-PEG10-THP is a PEG-based PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the solubility and stability of PROTACs, enabling the targeted degradation of specific proteins in cellular systems. THP-PEG10-THP is essential for researchers investigating protein regulation and therapeutic strategies for various diseases through targeted ubiquitination and proteasomal degradation.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTHP-PEG10-THP is a PEG-based PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the solubility and stability of PROTACs, enabling the targeted degradation of specific proteins in cellular systems. THP-PEG10-THP is essential for researchers investigating protein regulation and therapeutic strategies for various diseases through targeted ubiquitination and proteasomal degradation.
Product Information
Catalog NumA83456
FormulaC30H58O13
Molecular Weight626.77
CAS Number42749-29-1
SMILESC1(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC2CCCCO2)CCCCO1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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