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THRβ receptor agonist-1

Catalog No.: A85483
THRβ Receptor Agonist
THRβ receptor agonist-1 selectively activates the thyroid hormone receptor beta (THRβ), promoting its downstream metabolic and transcriptional pathways. This compound demonstrates significant biological activity in enhancing insulin sensitivity and regulating lipid metabolism. It is a valuable tool for research applications focused on metabolic disorders, thyroid function, and related endocrine studies.
THRβ receptor agonist-1 2403721-00-4 THRβ Receptor Agonist
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTHRβ receptor agonist-1 selectively activates the thyroid hormone receptor beta (THRβ), promoting its downstream metabolic and transcriptional pathways. This compound demonstrates significant biological activity in enhancing insulin sensitivity and regulating lipid metabolism. It is a valuable tool for research applications focused on metabolic disorders, thyroid function, and related endocrine studies.
Product Information
Catalog NumA85483
FormulaC18H12Cl2N6O4
Molecular Weight447.23
CAS Number2403721-00-4
SMILESN#CC1=NN(C2=CC(Cl)=C(C(Cl)=C2)OC3=NNC(C4=C3CCC4C)=O)C(NC1=O)=O
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Endocrinology-Hormones > Thyroid Hormone Receptor