THRβ receptor agonist-2

Catalog No.: A85506
THRβ Receptor Agonist
THRβ receptor agonist-2 is a selective agonist of the THRβ receptor, primarily involved in metabolic regulation. This compound exhibits potent biological activity in modulating lipogenesis and glucose metabolism, making it valuable for research into liver disorders and cardiometabolic diseases. Its role in enhancing insulin sensitivity and improving lipid profiles provides a basis for investigating therapeutic strategies in metabolic syndrome.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
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Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTHRβ receptor agonist-2 is a selective agonist of the THRβ receptor, primarily involved in metabolic regulation. This compound exhibits potent biological activity in modulating lipogenesis and glucose metabolism, making it valuable for research into liver disorders and cardiometabolic diseases. Its role in enhancing insulin sensitivity and improving lipid profiles provides a basis for investigating therapeutic strategies in metabolic syndrome.
Product Information
Catalog NumA85506
FormulaC17H15Cl2N5O5
Molecular Weight440.24
CAS Number2411677-11-5
SMILESO=C(C1=NC(ON1)=O)NC2=CC(Cl)=C(OC(C=C3C(C)C)=NN(C)C3=O)C(Cl)=C2
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