Fig. 1 · Structure

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Thymol blue

Acid-base Indicator

Thymol blue is a reversible pH indicator that targets acid-base conditions through protonation and deprotonation mechanisms. It exhibits distinct color changes, transitioning from red in acidic solutions (pH 1.2-2.8) to yellow and then to blue in alkaline environments (pH 8.0-9.6). Quantitative detection is facilitated by an absorption peak shift observed at 435 nm and 596 nm in the UV-visible spectrum. Thymol blue can also be immobilized in a silica gel matrix using sol-gel technology, enabling its application as a solid-state sensor for in-situ pH measurement in marine settings and acid-base monitoring in biomedical research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 76-61-9
Applications Acid-base Indicator
Formula C27H30O5S
Molecular Weight 466.59
Synonyms Thymolsulphonephthalein
SMILES
O=S1(OC(C2=C(C)C=C(O)C(C(C)C)=C2)(C3=C(C)C=C(O)C(C(C)C)=C3)C4=CC=CC=C41)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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