Fig. 1 · Structure
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TINK-IN-1
TNIK Inhibitor
TINK-IN-1 is a selective inhibitor of Traf2- and Nck-interacting kinase (TNIK) with an IC50 of 8 nM. This compound demonstrates significant inhibition of viability in colorectal cancer cells, making it a valuable tool for cancer research. Its specificity for TNIK allows for targeted investigations into pathways relevant to tumor growth and progression. TINK-IN-1 may be useful in studying the role of TNIK in various cellular processes and disease states.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1417795-25-5 |
| Applications | TNIK Inhibitor |
| Formula | C24H24N4O3 |
| Molecular Weight | 416.47 |
| SMILES | N#CC1=CC(C2=CC(NC3=CC=C(N4CCOCC4)C(OC)=C3)=NC=C2)=C(OC)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.