Fig. 1 · Structure
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TIQ-A
TNKS2 Inhibitor
TIQ-A is a potent inhibitor of TNKS2 (tankyrase 2), exhibiting an IC50 of 24 nM. This compound has shown promise as an anti-ischemic agent, potentially modulating pathways involved in ischemic injury. It serves as a valuable tool for research focused on cellular stress responses and the role of TNKS2 in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 420849-22-5 |
| Applications | TNKS2 Inhibitor |
| Formula | C11H7NOS |
| Molecular Weight | 201.24 |
| SMILES | O=C1NC2=C(C3=C1C=CC=C3)C=CS2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.