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Tirilazad mesylate hydrate

Antiviral Agent

Tirilazad mesylate hydrate is a non-glucocorticoid 21-aminosteroid that functions primarily as an antiviral agent by inhibiting lipid peroxidation. This compound exhibits significant neuroprotective properties, particularly in the context of brain and spinal cord injuries caused by trauma, stroke, and ischemia-reperfusion events. Tirilazad mesylate hydrate has demonstrated antiviral activity against novel coronavirus (nCoV) and is applicable for research into ischemic strokes and subarachnoid hemorrhage.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	111793-42-1
Applications	Antiviral Agent
Formula	C₃₉H₅₈N₆O₆S
Molecular Weight	738.98
Synonyms	U 74006F hydrate
SMILES	CS(=O)(O)=O.C[C@@]12[C@](C[C@H]([C@@H]2C(CN3CCN(C4=NC(N5CCCC5)=NC(N6CCCC6)=C4)CC3)=O)C)([H])[C@@]7([H])C([C@@]8(C(CC7)=CC(C=C8)=O)C)=CC1.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.