Fig. 1 · Structure
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Tirilazad
Antiviral Agent
Tirilazad is a nonglucocorticoid 21-aminosteroid that functions primarily as an antiviral agent by inhibiting lipid peroxidation. It demonstrates neuroprotective effects, particularly in models of ischemic stroke, and is effective in attenuating injuries associated with trauma, stroke, and ischemia/reperfusion events. Additionally, Tirilazad has shown antiviral activity against novel coronaviruses, making it a valuable reagent for research in subarachnoid hemorrhage and related neurological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 110101-66-1 |
| Applications | Antiviral Agent |
| Formula | C38H52N6O2 |
| Molecular Weight | 624.86 |
| Synonyms | U 74006F free base |
| SMILES | C[C@@]12[C@](C[C@H]([C@@H]2C(CN3CCN(C4=NC(N5CCCC5)=NC(N6CCCC6)=C4)CC3)=O)C)([H])[C@@]7([H])C([C@@]8(C(CC7)=CC(C=C8)=O)C)=CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.