Fig. 1 · Structure

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Tizetatug rezetecan

Anticancer Agent

Tizetatug rezetecan is an antibody-drug conjugate (ADC) designed to target and inhibit cancer cell proliferation. Comprising the antibody Tizetatug and the cytotoxic component MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan, this compound exhibits potent anticancer activity. It is primarily utilized for research applications focused on the treatment of various cancer types, particularly in studies evaluating targeted therapy efficacy and drug resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2938864-88-9
Applications Anticancer Agent
Synonyms SHR-A1921

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Customer Questions
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
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