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TLD-1433

Photodynamic Antiviral Agent

TLD-1433 is a fourth-generation ruthenium (II) based photodynamic compound (PDC) that functions as a photodynamic antiviral agent. Activated by green light at 525 ± 25 nm, it efficiently generates reactive oxygen species (ROS) to inactivate a broad range of pathogens. TLD-1433 significantly induces lipid peroxidation of viral membranes, targeting both enveloped viruses, such as H1N1 and coronaviruses, with ID50 values in the nanomolar range, and non-enveloped viruses, requiring micromolar concentrations for effective inactivation. Additionally, TLD-1433 possesses antigen retention properties and is suitable for preparing inactivated vaccines.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1471479-22-7
Applications	Photodynamic Antiviral Agent
Formula	C₄₉H₃₈Cl₂N₈RuS₃
Molecular Weight	1007.05
SMILES	CC1=CC=[N](C2=C1)[Ru+2]([N]3=CC=C4)([N](C5=C6)=CC=C6C)([N](C5=C7)=CC=C7C)([N](C2=C8)=CC=C8C)[N]9=CC=CC%10=C9C3=C4C%11=C%10NC(C%12=CC=C(C%13=CC=C(C%14=CC=CS%14)S%13)S%12)=N%11.[Cl-].[Cl-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.