TLR7 Agonist 14 (compound 17b) is a potent activator of Toll-like receptor 7 (TLR7) with an EC50 value of 18 nM. This compound effectively stimulates the activation of mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low nanomolar concentrations. Its significant biological activity makes it a valuable tool for research applications focused on immune modulation and inflammation pathways.
TLR7 Agonist 14 (compound 17b) is a potent activator of Toll-like receptor 7 (TLR7) with an EC50 value of 18 nM. This compound effectively stimulates the activation of mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low nanomolar concentrations. Its significant biological activity makes it a valuable tool for research applications focused on immune modulation and inflammation pathways.
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