TLR7 agonist 16

Catalog No.: A35477
TLR7 Agonist
TLR7 Agonist 16 is a potent agonist targeting Toll-like receptor 7 (TLR7) with an EC50 of 18 nM. It effectively stimulates the activation of mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations. This compound is valuable for research applications involving immune response modulation and the study of TLR7-associated pathways.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTLR7 Agonist 16 is a potent agonist targeting Toll-like receptor 7 (TLR7) with an EC50 of 18 nM. It effectively stimulates the activation of mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations. This compound is valuable for research applications involving immune response modulation and the study of TLR7-associated pathways.
Product Information
Catalog NumA35477
FormulaC25H29N5O2
Molecular Weight431.53
CAS Number2832199-56-9
SMILESO=C(OC(C)C)NC1=CC=C(CN2C(CCCC)=NC3=C2C4=CC=CC=C4N=C3N)C=C1
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