TLR8 Agonist 10 is a selective agonist targeting Toll-like receptor 8 (TLR8), demonstrating an EC50 of 0.019 μM in human cells. This compound activates TLR8-mediated signaling pathways, functioning as a latency-reversing agent that reactivates latent HIV-1 reservoirs. Additionally, TLR8 Agonist 10 enhances the activity of innate cytotoxic natural killer cells, allowing for targeted effects on HIV-infected CD4+ T cells. This reagent is valuable for research focused on HIV-1 infection and immune modulation.
TLR8 Agonist 10 is a selective agonist targeting Toll-like receptor 8 (TLR8), demonstrating an EC50 of 0.019 μM in human cells. This compound activates TLR8-mediated signaling pathways, functioning as a latency-reversing agent that reactivates latent HIV-1 reservoirs. Additionally, TLR8 Agonist 10 enhances the activity of innate cytotoxic natural killer cells, allowing for targeted effects on HIV-infected CD4+ T cells. This reagent is valuable for research focused on HIV-1 infection and immune modulation.
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