TMI-1

Catalog No.: A17212

TACE/MMP inhibitor

TMI-1

TMI-1 Chemical Structure

CAS NO. 287403-39-8

TMI-1 is a novel orally active dual inhibitor of ADAM17 (TACE) and MMP.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $520.00

Special Price $416.00

100 mg

Regular Price: $880.00

Special Price $704.00

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Biological Activity

TMI-1 is a novel orally active dual inhibitor of ADAM17 (TACE) and MMP.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.09 mL 125.47 mL 250.95 mL
0.5 mM 5.02 mL 25.09 mL 50.19 mL
1 mM 2.51 mL 12.55 mL 25.09 mL
5 mM 0.5 mL 2.51 mL 5.02 mL

*The above data is based on the productmolecular weight 398.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17212
Actions Inhibitor
CAS No. 287403-39-8
Formula C17H22N2O5S2
M. Wt 398.49
Purity >98%
Synonyms TMI 1, TMI1
SMILES O=C([[email protected]@H]1N(S(=O)(C2=CC=C(OCC#CC)C=C2)=O)CCSC1(C)C)NO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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