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TMP 269

Catalog No.: A14128

HDAC inhibitor

TMP 269

TMP 269 Chemical Structure

CAS NO. 1314890-29-3

TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$150.00
25 mg
$250.00
10mM * 1mL in DMSO
$110.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
In vitro DMSO 89 mg/mL (172.97 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.44 mL 97.18 mL 194.36 mL
0.5 mM 3.89 mL 19.44 mL 38.87 mL
1 mM 1.94 mL 9.72 mL 19.44 mL
5 mM 0.39 mL 1.94 mL 3.89 mL

*The above data is based on the productmolecular weight 514.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14128
Actions Inhibitor
CAS No. 1314890-29-3
Formula C25H21F3N4O3S
M. Wt 514.52
Purity >98%
Synonyms TMP-269,TMP269
SMILES O=C(c1cccc(c1)c1noc(n1)C(F)(F)F)NCC1(CCOCC1)c1scc(n1)c1ccccc1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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