HDAC4

Cat. No.

A14326

CAS No.

1314891-22-9

TMP 195

TMP195 is the most potent and selective class IIa HDAC inhibitor.

Cat. No.

A18899

CAS No.

1629729-98-1

CHDI-390576

CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histonedeacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform.

Cat. No.

A19615

CAS No.

2225728-57-2

FT895

FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM.

Cat. No.

A11920

CAS No.

128517-07-7

Romidepsin (FK228, Depsipeptide)

Synonyms: FK228; Depsipeptide

Romidepsin strongly inhibits HDAC1 and HDAC2 with IC5N/A of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC5N/A 25 nM and 79N/A nM, respectively.

Cat. No.

A10518

CAS No.

404950-80-7

Panobinostat (LBH589)

Synonyms: NVP-LBH589; LBH589

LBH589 is a hydroxamic acid and acts as a non-selective HDAC inhibitor with IC5o of HDAC1 to be 0.23 nM.