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TNF-α-IN-22

TNFα Inhibitor

TNF-α-IN-22 is a TNFα inhibitor that interferes with the downregulation of IkBα, leading to apoptosis and cell cycle arrest. This compound exhibits significant biological activity in studies related to inflammation and is particularly relevant in the investigation of triple-negative breast cancer. Its mechanism of action makes it a valuable tool for elucidating TNFα's role in cancer progression and therapeutic resistance.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2251689-60-6
Applications	TNFα Inhibitor
Formula	C₁₃H₁₁NO₃
Molecular Weight	229.23
SMILES	COC1=CC2=CC=CC=C2C(/C=C/[N+]([O-])=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.