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TNF-α-IN-24

TNF-α Inhibitor

TNF-α-IN-24 is a potent tumor necrosis factor-alpha (TNF-α) inhibitor with an IC50 of 4.1 nM. This compound is valuable for investigating the mechanisms underlying inflammatory and autoimmune disorders, particularly in models of rheumatoid arthritis and Crohn’s disease. Its specificity for TNF-α allows for targeted research in cytokine modulation and potential therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3075686-66-4
Applications	TNF-α Inhibitor
Formula	C₂₇H₂₄F₂N₆O₂
Molecular Weight	502.52
SMILES	CN([C@H]1C2=NN(C=CC(C3=CN=C(C4(CCC4)N)N=C3)=C5)C5=C2[C@@H](C6=C(OC(F)F)C=CC=C67)C1)C7=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.