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TNF-α-IN-26

TNF-α Inhibitor

TNF-α-IN-26 is a selective inhibitor of tumor necrosis factor-alpha (TNF-α), exhibiting an IC50 of 0.10 μM against CSBP ligands. This compound effectively inhibits LPS-stimulated TNF production in mouse models, making it a valuable tool for studying the mechanisms of inflammation. TNF-α-IN-26 is particularly relevant for research focused on inflammatory diseases and related therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	165806-63-3
Applications	TNF-α Inhibitor
Formula	C₁₉H₂₀FN₃O
Molecular Weight	325.38
SMILES	FC1=CC=C(C2=C(C3=CC=NC=C3)N(CCCOCC)C=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.