Fig. 1 · Structure
Documents & Downloads
TNF-α-IN-6
TNF Receptor Inhibitor
TNF-α-IN-6 is an allosteric inhibitor of the tumor necrosis factor-alpha (TNFα) receptor, demonstrating a dissociation constant (KD) of 6.8 nM. This compound exhibits significant anti-inflammatory properties, making it a valuable tool in research applications focused on inflammatory diseases and cytokine signaling pathways. Its oral bioavailability allows for convenient use in various experimental settings.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2699704-20-4 |
| Applications | TNF Receptor Inhibitor |
| Formula | C26H25N9O2 |
| Molecular Weight | 495.54 |
| SMILES | N#CC1=NC=CC=C1CN(C2=NC(C3=CN=C(N4C[C@]5([H])N(C(NC5)=O)CC4)N=C3)=CC=C26)C(C)(C)C6=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.