Fig. 1 · Structure

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TNIK-IN-8

TNIK Inhibitor

TNIK-IN-8 is a potent and selective inhibitor of TNIK (T-cell activated nuclear protein 1), demonstrating an IC50 value of 6 nM. This compound exhibits significant antitumor activity, making it a valuable tool for cancer research. Its ability to modulate TNIK pathways facilitates investigations into cellular signaling processes and their implications in tumorigenesis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3068941-89-6
Applications TNIK Inhibitor
Formula C24H20FN3O
Molecular Weight 385.43
SMILES
CC(O)(C)C#CC1=CC(C=C(C2=C(C3=CC=C(F)C=C3)N=CN2C)C=C4)=C4N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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