TNIK&MAP4K4-IN-1 is a potent dual inhibitor targeting TNIK and MAP4K4/HGK, demonstrating IC50 values of 1.29 nM and less than 10 nM, respectively, in human hepatic stellate cell line LX-2. This compound exhibits significant biological activity in inhibiting pathways associated with cancer and fibrotic processes. It serves as a valuable tool for researchers studying the roles of TNIK and MAP4K4 in cellular signaling and disease progression.
TNIK&MAP4K4-IN-1 is a potent dual inhibitor targeting TNIK and MAP4K4/HGK, demonstrating IC50 values of 1.29 nM and less than 10 nM, respectively, in human hepatic stellate cell line LX-2. This compound exhibits significant biological activity in inhibiting pathways associated with cancer and fibrotic processes. It serves as a valuable tool for researchers studying the roles of TNIK and MAP4K4 in cellular signaling and disease progression.
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