Fig. 1 · Structure
Documents & Downloads
Topotecan hydrochloride hydrate
Topo I Inhibitor
Topotecan hydrochloride hydrate is a potent inhibitor of Topoisomerase I, an enzyme crucial for DNA replication and cell division. This compound induces cell cycle arrest in the G0/G1 and S phases, promoting apoptosis in cancer cells. Topotecan hydrochloride hydrate is primarily utilized in research applications aimed at investigating its anticancer effects and mechanisms of action in various tumor models.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1044663-62-8 |
| Applications | Topo I Inhibitor |
| Formula | C23H26ClN3O6 |
| Molecular Weight | 475.92 |
| Synonyms | SKF 104864A hydrochloride hydrate; NSC 609669 hydrochloride hydrate |
| SMILES | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.Cl.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.