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Tos-aminoxy-Boc-PEG4-Tos

PROTAC Linker

Tos-aminoxy-Boc-PEG4-Tos is a PEG-based linker specifically designed for PROTAC (proteolysis-targeting chimera) applications. This compound facilitates the synthesis of PROTACs by enabling the conjugation of target proteins with E3 ligases, thus promoting targeted degradation pathways. Its unique structure enhances solubility and stability, making it a valuable tool for researchers investigating protein regulation mechanisms and drug discovery processes.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1817735-42-4
Applications	PROTAC Linker
Formula	C₂₇H₃₉NO₁₁S₂
Molecular Weight	617.73
SMILES	O=S(N(OCCOCCOCCOCCOS(=O)(C1=CC=C(C)C=C1)=O)C(OC(C)(C)C)=O)(C2=CC=C(C)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.