Fig. 1 · Structure

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Tos-O-C4-NH-Boc

PROTAC Linker

Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker that facilitates the synthesis of PROTAC molecules. This compound serves as a key building block in the development of targeted protein degradation strategies, enabling the selective modulation of protein levels in cellular systems. It is particularly useful in research applications focused on enhancing therapeutic efficacy through innovative drug design.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 180851-50-7
Applications PROTAC Linker
Formula C16H25NO5S
Molecular Weight 343.44
SMILES
O=C(OC(C)(C)C)NCCCCOS(=O)(C1=CC=C(C)C=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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