Fig. 1 · Structure
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Tos-PEG1-CH2-Boc
PROTAC Linker
Tos-PEG1-CH2-Boc is a polyethylene glycol (PEG)-based linker designed for the development of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of target ligands to E3 ligase recruiters, enhancing the effectiveness of targeted protein degradation. Its biochemical properties support various applications in chemical biology and protein modulation research, making it a valuable tool in drug discovery and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1643957-24-7 |
| Applications | PROTAC Linker |
| Formula | C15H22O6S |
| Molecular Weight | 330.40 |
| SMILES | O=C(OC(C)(C)C)COCCOS(=O)(C1=CC=C(C)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.