Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker designed for use in protein degradation research. This compound features an alkyne functional group, enabling its role as a click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing partners. It is instrumental in the synthesis of Thalidomide-O-PEG2-propargyl, facilitating advancements in targeted protein degradation studies.
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker designed for use in protein degradation research. This compound features an alkyne functional group, enabling its role as a click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing partners. It is instrumental in the synthesis of Thalidomide-O-PEG2-propargyl, facilitating advancements in targeted protein degradation studies.
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