Fig. 1 · Structure
Documents & Downloads
Tos-PEG2-O-Propargyl
PROTAC Linker
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker designed for use in protein degradation research. This compound features an alkyne functional group, enabling its role as a click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing partners. It is instrumental in the synthesis of Thalidomide-O-PEG2-propargyl, facilitating advancements in targeted protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1119249-30-7 |
| Applications | PROTAC Linker |
| Formula | C14H18O5S |
| Molecular Weight | 298.35 |
| SMILES | C#CCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.