TP-050 is a potent, orally active NMDAR agonist, selectively targeting the GluN2A and GluN2D subtypes with EC50 values of 0.51 μM and 9.6 μM, respectively. This compound effectively crosses the blood-brain barrier, facilitating its role in enhancing hippocampal long-term potentiation and promoting neuronal signal transmission. TP-050 offers valuable applications in neuroscience research, particularly in studies involving synaptic plasticity and cognitive function.
TP-050 is a potent, orally active NMDAR agonist, selectively targeting the GluN2A and GluN2D subtypes with EC50 values of 0.51 μM and 9.6 μM, respectively. This compound effectively crosses the blood-brain barrier, facilitating its role in enhancing hippocampal long-term potentiation and promoting neuronal signal transmission. TP-050 offers valuable applications in neuroscience research, particularly in studies involving synaptic plasticity and cognitive function.
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