Fig. 1 · Structure

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TP receptor antagonist-1

TP receptor antagonist

TP receptor antagonist-1 is a selective antagonist of the thromboxane A2 receptor (TP receptor), exhibiting IC50 values of 9.46 μM for TPa and 8.49 μM for TPb. This compound plays a significant role in modulating thromboxane-related signaling pathways, making it valuable for investigating cardiovascular diseases. Researchers can utilize TP receptor antagonist-1 to explore therapeutic strategies targeting TP receptor-mediated effects in various cardiovascular conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1448452-21-8
Applications TP receptor antagonist
Formula C17H16ClN3O4S
Molecular Weight 393.84
SMILES
CC(NC(NS(=O)(C1=C(OC2=CC=C(Cl)C=C2)C=CC(C#N)=C1)=O)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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