Fig. 1 · Structure

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TP receptor antagonist-2

TP Receptor Antagonist

TP Receptor Antagonist-2 is a selective thromboxane A2 receptor (TP receptor) antagonist, exhibiting IC50 values of 5.64 μM and 5.27 μM for the TPα and TPβ isoforms, respectively. This compound effectively inhibits platelet aggregation, making it a valuable tool for research into cardiovascular conditions and thrombotic disorders. Its application in studying TP receptor signaling pathways enhances understanding of related physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1448452-22-9
Applications TP Receptor Antagonist
Formula C18H18ClN3O4S
Molecular Weight 407.87
SMILES
CC(C)(NC(NS(=O)(C1=C(OC2=CC=C(Cl)C=C2)C=CC(C#N)=C1)=O)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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