Fig. 1 · Structure
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TP receptor antagonist-3
TP Receptor Antagonist
TP Receptor Antagonist-3 (compound 51280) is a potent antagonist of the thromboxane A2 receptor (TP), exhibiting an IC50 of 15.7 nM against human TP. This compound is valuable for investigating disease mechanisms in Alzheimer's disease, cardiovascular conditions, and respiratory disorders, as well as cancer research applications. Its ability to selectively inhibit TP receptor signaling makes it an important tool for exploring therapeutic interventions in these areas.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 165537-72-4 |
| Applications | TP Receptor Antagonist |
| Formula | C19H19ClNNaO4S |
| Molecular Weight | 415.87 |
| SMILES | O=C(CCC1=CC=CC2=C1CCC(C2)NS(=O)(C3=CC=C(C=C3)Cl)=O)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.