TP-TRFS

Catalog No.: A77993
Two-Photon Fluorescent TrxR Probe
TP-TRFS is a selective two-photon fluorescent probe designed to target thioredoxin reductase (TrxR). Its primary mechanism involves the detection of TrxR activity through fluorescence, making it a valuable tool for studying redox biology. This probe is particularly useful for research applications involving oxidative stress, cellular signaling, and cancer biology, enabling real-time monitoring of TrxR in live cells.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTP-TRFS is a selective two-photon fluorescent probe designed to target thioredoxin reductase (TrxR). Its primary mechanism involves the detection of TrxR activity through fluorescence, making it a valuable tool for studying redox biology. This probe is particularly useful for research applications involving oxidative stress, cellular signaling, and cancer biology, enabling real-time monitoring of TrxR in live cells.
Product Information
Catalog NumA77993
FormulaC16H15NO3S2
Molecular Weight333.43
CAS Number2937819-61-7
SMILESCC(C1=CC=C2C=C(C=CC2=C1)NC(OC3CSSC3)=O)=O
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