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TPα/β antagonist-1

TPα/β Antagonist

TPα/β antagonist-1 is a selective antagonist of the thromboxane A2 receptors TPα and TPβ, exhibiting IC50 values of 1.52 nM and 0.79 nM, respectively. This compound effectively inhibits U-46619-induced intracellular calcium mobilization and reduces platelet aggregation. TPα/β antagonist-1 is valuable for investigating mechanisms underlying cardiovascular diseases and evaluating potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	899789-84-5
Applications	TPα/β Antagonist
Formula	C₂₀H₂₃N₃O₆S
Molecular Weight	433.48
SMILES	O=C(NC1CCCCC1)NS(=O)(C2=CC([N+]([O-])=O)=CC=C2OC3=CC=C(C=C3)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.