Fig. 1 · Structure

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TR modulator-1

TR Modulator

TR modulator-1 is a selective thyroid hormone receptor (TR) modulator. This compound exhibits significant biological activity in modulating TR signaling, making it valuable for studying disorders such as hyperthyroidism and thyrotoxicosis. TR modulator-1 aids in the exploration of therapeutic pathways and mechanisms involved in thyroid hormone regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1073180-47-8
Applications TR Modulator
Formula C21H20F3N5O4
Molecular Weight 463.41
SMILES
O=C(N1NC(CC12CCN(CC2)C3=CC=C([N+]([O-])=O)C=C3)=O)NC4=CC=CC(C(F)(F)F)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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