Biological Activity
Tradipitant, also known as VLY-686 and LY686017, is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.01 mL | 85.05 mL | 170.1 mL |
0.5 mM | 3.4 mL | 17.01 mL | 34.02 mL |
1 mM | 1.7 mL | 8.5 mL | 17.01 mL |
5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
*The above data is based on the productmolecular weight 587.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16918 |
---|---|
Actions | Antagonist |
M. Wt | 587.9 |
Formula | C28H16ClF6N5O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 622370-35-8 |
Synonyms | LY-686017, LY 686017, LY686017, VLY 686, VLY686, VLY-686 |
SMILES | O=C(C1=CC=CN=C1C2=C(C3=CC=NC=C3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=N2)C5=CC=CC=C5Cl |
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