Fig. 1 · Structure

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Trandolapril hydrochloride

ACE Inhibitor

Trandolapril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor that exhibits antihypertensive and cardioprotective properties. Upon administration, it is hydrolyzed to its active diacid form, enhancing its efficacy in lowering blood pressure and improving outcomes in conditions such as hypertension, congestive heart failure (CHF), and post-myocardial infarction (MI). This compound serves as a valuable tool in cardiovascular research and pharmacological studies related to ACE inhibition.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 87725-72-2
Applications ACE Inhibitor
Formula C24H35ClN2O5
Molecular Weight 467.00
Synonyms RU44570 hydrochloride
SMILES
O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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