Fig. 1 · Structure
Documents & Downloads
Trandolapril
ACE Inhibitor
Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor that is converted to its active form, Trandolaprilat, through hydrolysis. This prodrug is primarily utilized in the management of hypertension, congestive heart failure (CHF), and post-myocardial infarction (MI) recovery. Its inhibition of the ACE pathway results in decreased production of angiotensin II, leading to vasodilation and reduced blood pressure. Trandolapril is widely used in cardiovascular research to explore mechanisms of hypertension and heart failure therapy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 87679-37-6 |
| Applications | ACE Inhibitor |
| Formula | C24H34N2O5 |
| Molecular Weight | 430.54 |
| Synonyms | RU44570 |
| SMILES | O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.