Fig. 1 · Structure
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Trandolaprilate hydrate
ACE Inhibitor
Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor primarily known for its role in regulating blood pressure. As the main bioactive metabolite of Trandolapril, Trandolaprilate hydrate effectively inhibits angiotensin-I-mediated c-fos induction. Its high lipophilicity enhances its biological activity and makes it a valuable reagent in cardiovascular research and related pharmacological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 951393-55-8 |
| Applications | ACE Inhibitor |
| Formula | C22H32N2O6 |
| Molecular Weight | 420.50 |
| Synonyms | Trandolaprilat hydrate; RU 44403 hydrate |
| SMILES | O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.